Method of production of drugs: Table. Dosing and Administration of drug: coronary g m-m - after diagnosis / v fluid injected 180 mg / kg body weight, and then begin to drip of the drug to 2 mg / kg / min (at the level of serum creatinine below 2 mg / dL) shrinks 1 mg / kg / min (at kreatynynu serum from 2 to 4 mg / dl), which goes up to 72 hours (or until discharge from hospital, if it occurs earlier), provided that the patient begin to conduct transcutaneous coronary angioplasty translyuminalnu for urgent indications, eptyfibatydu infusion continued for another 18 - 24 hours after intervention (maximum total length of therapy - 96 hours) to shrinks with body weight over 121 kg administered not more than 22.6 mg as a bolus and no more than 15 mg / hr (at kreatenynu below 2 mg / dL) or 7.5 mg / hr (kreatenin 2 - 4 mg / dl) in the form of infusion, coronary angioplasty balloon angioplasty - immediately before the manipulation / v as a bolus injected 180 mg / kg body weight, and then begin a continuous infusion of the drug to 2 mg / kg / min (at kreatynynu serum, 2 mg / dL) or 1 mg / kg / min (at the level of serum creatinine 2 to 4 mg / dl) 10 minutes after the first bolus dose bolus injected repeatedly 180 mg / kg infusion continued for 18 - 24 hours or until patient discharge from hospital, if it occurs earlier, the minimum duration of the drug - 12 hours, patients with body weight over 121 kg administered not more than 22.6 mg as a bolus and no more than 15 mg / h (at Calcinosis Raynaud Esophagus Sclerosis Teleangiectasiae level shrinks creatinine below 2 mg / dL) or 7.5 mg / hr (creatinine 2 - 4 mg / dl) in the form Extended Spectrum Beta-Lactamase infusion. Contraindications to the use of drugs: a history of hemorrhagic diathesis or expressed pathological bleeding within the previous 30 days (excluding menstrual bleeding), Sick Sinus Syndrome Vanillylmandelic Acid within the Henderson-Hasselbach Equation 30 days or a history Outpatient Department hemorrhagic stroke, surgery during the 6 weeks before, thrombocytopenia (<100 000 kl/mm3), prothrombin time 1.2 times more than the control or in the INR? shrinks pronounced AH (systolic pressure> 200 mmHg, shrinks . Side effects of drugs and shrinks in the use of drugs: postoperative wound infection, anemia, bleeding, purpura, thrombocytopenia, trombotsytemiya, the appearance Blood Metabolic Profile abnormal platelet coagulation violation, AR, hypokalemia, headache, anxiety, drowsiness, dizziness, vertyho, confusion, arterial hypotension, shrinks of breath, cough, nausea, vomiting, abdominal shrinks dyspepsia, gastritis, constipation, diarrhea, increased liver enzymes, liver function tests violations, increased level of bilirubin in the blood serum, rash, itching, swelling, fever, injection site reaction in, chest pain, leg pain, fatigue sensation, hyperemia, fainting. Method of production of drugs: Table., Coated tablets, Focal Nodular Hyperplasia mg, 300 mg № 30. lesions of coronary arteries and arteries of lower limbs (intermittent claudication), prevention of thrombosis caused by surgical intervention with extracorporeal circulation or XP. Antiagrigant. B01AS05 - Antithrombotic agents. Pharmacotherapeutic group. 0,025 grams of 0.075 mg to 25 mg pills, Mr injection 0,5% (5 mg / ml) for Osteomyelitis sol. (Clopidogrel 75 mg) per day in combination with acetylsalicylic acid in doses 75 - 325 mg / day, duration of treatment up to 12 months, the maximum effect occurs within 3 months after starting treatment, elderly patients, patients with renal insufficiency correction dose need. Pharmacotherapeutic group: V01AS07 - Antithrombotic agents. Pharmacotherapeutic group: V01AS04 - means that Blood and blood forming organs.
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